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Created page with '{{Drugswitch | from = maprotiline | to = trazodone | stop = * '''Before day 0:''' gradually reduce dosage of maprotiline to a maximum of 50 mg/ day, when this dosage is > 50 ...'
{{Drugswitch
| from = maprotiline
| to = trazodone
| stop =
* '''Before day 0:''' gradually reduce dosage of maprotiline to a maximum of 50 mg/ day, when this dosage is > 50 mg/day.
* '''Day 1:''' reduce dosage of maprotiline to 25 mg/day.
* '''Day 8:''' stop administration of maprotiline.
| start =
No wash-out period is needed.
* '''Day 1:''' simultaneously start administration of trazodone in a dosage of 150 mg/day.
* '''Day 8:''' continue only administration of trazodone. If necessary, increase the dosage of trazodone to a maximum of 400 mg/day.
| info =
* Occurrence of the serotonin syndrome is theoretically possilble, so caution is necessary.}}
| from = maprotiline
| to = trazodone
| stop =
* '''Before day 0:''' gradually reduce dosage of maprotiline to a maximum of 50 mg/ day, when this dosage is > 50 mg/day.
* '''Day 1:''' reduce dosage of maprotiline to 25 mg/day.
* '''Day 8:''' stop administration of maprotiline.
| start =
No wash-out period is needed.
* '''Day 1:''' simultaneously start administration of trazodone in a dosage of 150 mg/day.
* '''Day 8:''' continue only administration of trazodone. If necessary, increase the dosage of trazodone to a maximum of 400 mg/day.
| info =
* Occurrence of the serotonin syndrome is theoretically possilble, so caution is necessary.}}