| to = bupropion
| stop =
* Gradually decrease the dosage of tranylcypromine with 10-20 mg/week. * When a dosage of 10 mg/day is reached, stop administration.{{stopTranyl}}
| start =
* '''Day 1-1410:''' a wash-out period start administration of two weeks is necessary. * '''Day 15:''' start bupropion after this period in a normal dosage of 150 mg/dayand gradually increase dose as necessary.
| info =
* Occurence of the serotonin syndrome is possible without a wash-out period.{{Tcrestore}}<ref name="informatorium">{{KNMP|tranylcypromine}}</ref>* The wash-Tranylcypromine has to be phased out period is necessary for the MAO enzymes to restore their functionavoid withdrawal symptoms.<ref>Dr. M.J.Blom et al. (2009) Gebruik van klassieke MAO-remmers</ref>}}