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| to = amitriptyline
| stop =
* '''Day 0:''' gradually reduce dosage of fluvoxamine to a maximum of 50 100 mg/ day when this the dosage is > 50 100 mg/day. * '''Day 1:''' reduce dosage of fluvoxamine to a maximum of 25 50 mg/day. * '''Day 8:''' stop administration of fluvoxamine
| start =
Caution is necessary.
* '''Day 1:''' simultaneously start administration of amitriptyline in a low dosage of 25 mg/day.
* '''Day 8:''' stop administration of fluvoxamine and continue administration of amitriptyline in a dosage of 50 mg/day.
* Start low, go slow!
| info =
* Fluvoxamine slows the metabolism of amitriptyline via CYP1A2 and CYP2D6.}}