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| to = amitriptyline
| stop =
* '''Day 0:''' Gradually reduce dosage of fluoxetine to a maximum of 20 mg/ day, when this dosage is > 20 mg/day. * '''Day 1:''' When a dosage of 20 mg/day is reached, stop administration.
| start =
Caution is necessary for at least four weeks.
* '''Day 1-8:''' start administration of amitriptyline in a low dosage of 25 mg/daywash-out period.* '''Day 8:''' increase start administration of amitriptyline in a low dosage of amitriptyline to 50 25 mg/day.*
* '''Day 15:''' if necessary, increase dosage of amitriptyline to 50-150 mg/day.
| info =
* Fluoxetine slows the metabolism of amitriptyline via CYP2D6.
* Start low, go slow for amitriptyline.}}