Changes

Trazodone-sertraline

108 bytes removed, 12:40, 10 July 2009

no edit summary

| stop =

* '''Before day 0:''' gradually reduce dosage of trazodone to a maximum of 150 mg/day, when this dosage is > 150 mg/day.

* '''Day 1:''' reduce dosage of trazodone to 75 -100 mg/day.

* '''Day 8:''' stop administration of trazodone.

* '''Day 8-13:''' wash-out period

| start =

* A wash-out period is not necessary, but care is needed.* '''Day 814:''' start administration of sertraline in a normal dosage of 50 mg/day.

| info =

* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.* Sertraline dose-dependently inhibits CYP2D6, which metabolizes trazodone.}}

Walter

editor, reviewer

1,499

edits

Psychiatrienet β

Changes

Trazodone-sertraline

Psychiatrienet ^β