* '''Day 0:''' gradually reduce dosage of venlafaxine to a maximum of 75 mg/ day.* '''Day 1:''' reduce a dosage of 75 mg/day to 37,5 mg/day.* '''Day 8:''' stop administration of venlafaxine. {{downVenla}}
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* '''Day 1:''' simultaneously start administration of amitriptyline in a low dosage of 25 mg/day.