* '''Day 115:''' simultaneously start administration of dosulepine in a low dosage of 50-75 25 mg/day. * '''Day 8:''' stop administration of venlafaxine and continue administration of dosulepine.| info = * “Start low, go slow” is not required, but caution with this switch is necessary.* Venlafaxine is a weak inhibitor of CYP2D6, which metabolizes dosulepine.}}