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* When a dosage of 20 mg/day is reached, stop administration.
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* '''Day 1-28:''' no administration of fluoxetine and bupropion (“wash-out” period in a low dosage of one 150 mg/day).* '''Day 229 en on:''' start administration of if necessary increase bupropion in a low dosage of 150 to 300 mg/day.
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