| to = sertraline
| stop =
* '''Before day 0:''' gradually reduce dosage of nortriptyline to a maximum of 100 mg/day.* '''Day 1:''' reduce dosage of nortriptyline to 50 mg/day.* '''Day 3:''' reduce dosage of nortriptyline to 25 mg/day.{{TCAdecrease25p3d}}| start = {{StartAntidepressant}}* '''Day 1:''' simultaneously start administration of sertraline in a normal dosage of 50 mg/day.| info =* '''Day 8:''' stop administration of nortriptyline and continue administration of Safe target dose sertraline in a dosage of 50-= 100 mg/day.| info = * Sertraline is a weak inhibitor of [[:wp:CYP2D6|CYP2D6]], which metabolizes nortriptyline.
}}