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* '''Before day 0:''' gradually reduce dosage of maprotiline to a maximum of 50 75 mg/ day, when this .* '''Day 1:''' reduce dosage is > of maprotiline to 50 mg/day. * '''Day 17:''' reduce dosage of maprotiline to 25 mg/day.* '''Day 814:''' stop administration dosage of maprotiline.
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No wash-out period is needed.
* '''Day 17:''' simultaneously start administration of trazodone in a dosage of 150 mg/day.* '''Day 814:''' continue trazodone. {{upTrazo}}
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