* '''Before day 0:''' gradually reduce dosage of maprotiline to a maximum of 75 mg/ day, when this dosage is > 75 mg/day.* '''Day 1-3:''' reduce dosage of maprotiline to 50 mg/day.* '''Day 4-7:''' reduce dosage of maprotiline to 25 mg/day.* '''Day 814:''' stop administration dosage of maprotiline.

* '''Day 814-2128:''' a wash-out period of two weeks is necessary.* '''Day 2229:''' start administration of tranylcypromine in a low dosage of 20 mg/day for one week.* '''Day 2936:''' after this week the dosage of tranylcypromine can be increased if necessary.}}