* '''Day 0: ''' gradually reduce dosage of citalopram/escitalopram to a maximum of 20 mg/day resp. 10 mg/day, when this dosage is respectively > 20 mg/day and > 10 mg/day. * '''Day 1: ''' reduce dosage of citalopram/escitalopram to a maximum of 10 mg/day resp. 5 mg/day. * '''Day 8: ''' stop administration of citalopram/escitalopram.

* '''Day 8: ''' no wash-out period is needed. Start administration of clomipramine in a low dosage of 50-75 mg/day.