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Citalopram-fluvoxamine

329 bytes removed, 20 February
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* Gradually reduce dosage of citalopram/escitalopram to a maximum of 20 mg/ day resp. 10 mg/day, when this dosage is respectively > 20 mg/day and > 10 mg/day. * When a dosage of 20 mg/day, resp. 10 mg/day, is reached, stop administration.{{TCAdecrease25p3d}}
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* No wash-out period is needed.* Start fluvoxamine the next day in normal dosage of 50 mg/day.{{StartfluvoxIA}}
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* The same applies to [[escitalopram]]Fluvoxamine is an inhibitor of CYP2C19, which metabolize citalopram.* {{theorSS}}* Fluvoxamine slows the metabolism of (es)citalopram by inhibition of CYP2C19 and CYP3A4Safe target dose fluvoxamine = 100 mg
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