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* '''Before day 1:''' gradually reduce dosage of clomipramine to a maximum of 50 mg/day.
* '''Day 1:''' reduce dosage of clomipramine to 25 mg/day.
* '''Day 38:''' reduce dosage of stop clomipramine to 10 mg/day.
| start =
* '''Day 18:''' simultaneously start administration of mianserine in a low dosage of 30 mg/day.* '''Day 815:''' stop administration of clomipramine and continue administration of mianserine. * If if necessary, increase dosage of mianserine.
}}