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Created page with '{{Drugswitch | from = amitriptyline | to = sertraline | stop = * '''Before day 0:''' gradually reduce dosage of amitriptyline to a maximum of 25-50 mg/day. * '''Day 1:''' redu...'
{{Drugswitch
| from = amitriptyline
| to = sertraline
| stop =
* '''Before day 0:''' gradually reduce dosage of amitriptyline to a maximum of 25-50 mg/day.
* '''Day 1:''' reduce dosage of amitriptyline to 25 mg/day.
* '''Day 3:''' reduce dosage of amitriptyline to 10 mg/day.
| start =
* '''Day 1:''' simultaneously start administration of sertraline in a normal dosage of 50 mg/day.
* '''Day 8:''' stop administration of amitriptyline and continue administration of sertraline.
| info =
* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.}}
| from = amitriptyline
| to = sertraline
| stop =
* '''Before day 0:''' gradually reduce dosage of amitriptyline to a maximum of 25-50 mg/day.
* '''Day 1:''' reduce dosage of amitriptyline to 25 mg/day.
* '''Day 3:''' reduce dosage of amitriptyline to 10 mg/day.
| start =
* '''Day 1:''' simultaneously start administration of sertraline in a normal dosage of 50 mg/day.
* '''Day 8:''' stop administration of amitriptyline and continue administration of sertraline.
| info =
* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.}}