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Trazodone-escitalopram

704 bytes added, 23:54, 4 March 2010
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#redirect [[Trazodone{{ Drugswitch | from = trazodone| to = escitalopram | stop = * '''Before day 1:''' gradually reduce dosage of trazodone to a maximum of 150 mg/day, when this dosage is > 150 mg/day. * '''Day 1:''' reduce dosage of trazodone to 75-citalopram]]100 mg/day.* '''Day 8:''' stop administration of trazodone.| start = * A wash-out period is not necessary, but care is needed.* '''Day 8:''' start administration of escitalopram in a normal dosage of 10 mg/day.| info = * Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.* Escitalopram is a weak inhibitor of CYP2D6, which metabolizes trazodone.* The content of trazodone in the tablet, for example 100 mg or 150 mg, determines which exact doses are given. }}
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