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* A wash-out period is not necessary.
* Start administration of nortriptyline the next day in a dosage of 50 mg/day.
* If necessary, increase dosage of nortriptyline with.<ref name="agoswitch"> {{Pubmed|20196187|McAllister-Williams RH et al. The use of antidepressants in clinical practice: focus on agomelatine. Hum Psychopharmacol. 2010 Mar 1;25(2):95-102}}</ref>}}