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Created page with '{{Drugcombi | base = risperidone | add = lithium | info = * Risperidone is principally metabolized by CYP2D6 to an active metabolite. * Lithium is eliminated by the kidney for a...'
{{Drugcombi
| base = risperidone
| add = lithium
| info =
* Risperidone is principally metabolized by CYP2D6 to an active metabolite.
* Lithium is eliminated by the kidney for about 95%. Changes in the rate of excretion can cause unwanted effects.
* This combination of drugs may have possible synergistic effects. However, this combination will also have additive side effects. Dose adaptation will be recommended for this combination.
| start =
* Start lithium according to the general dosing advice.
| cave =
* The concomitant administration of lithium with neuroleptic agents may increase the risk of extrapyramidal reactions and neurotoxicity.
}}
| base = risperidone
| add = lithium
| info =
* Risperidone is principally metabolized by CYP2D6 to an active metabolite.
* Lithium is eliminated by the kidney for about 95%. Changes in the rate of excretion can cause unwanted effects.
* This combination of drugs may have possible synergistic effects. However, this combination will also have additive side effects. Dose adaptation will be recommended for this combination.
| start =
* Start lithium according to the general dosing advice.
| cave =
* The concomitant administration of lithium with neuroleptic agents may increase the risk of extrapyramidal reactions and neurotoxicity.
}}