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Fluoxetine-maprotiline

599 bytes added, 19:32, 3 May 2009
Created page with '{{Drugswitch | from = fluoxetine | to = maprotiline | stop = * Gradually reduce dosage of fluoxetine to a maximum of 20 mg/ day, when this dosage is > 20 mg/day. * When a dos...'
{{Drugswitch
| from = fluoxetine
| to = maprotiline
| stop =
* Gradually reduce dosage of fluoxetine to a maximum of 20 mg/ day, when this dosage is > 20 mg/day.
* When a dosage of 20 mg/day is reached, stop administration.
| start =
Caution is necessary for at least four weeks.
* '''Day 1:''' start administration of maprotiline in a low dosage of 25 mg/day.
* '''Day 8:''' increase dosage of maprotiline to 50 mg/day.
* '''Day 15:''' increase dosage of maprotiline to 75 mg/day.
| info =
* Fluoxetine slows the metabolism of maprotiline via CYP2D6.
* Start low, go slow for maprotiline.}}
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