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* '''Before day 1:''' gradually reduce dosage of fluvoxamine to a maximum of 50 mg/ day when this dosage is > 50 mg/day.
* '''Day 1:''' reduce dosage of fluvoxamine to a maximum of 25 mg/day. * '''Day 8:''' stop administration of fluvoxamine
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Caution is necessary.
* '''Day 1:''' simultaneously start administration of clomipramine in a low dosage of 25-50 mg/day.
* '''Day 8:''' stop administration of fluvoxamine and continue administration of clomipramine in a dosage of 50-75 mg/day.
* Start low, go slow!
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