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Created page with '{{Drugswitch | from = fluvoxamine | to = doxepin | stop = * '''Day 0:''' gradually reduce dosage of fluvoxamine to a maximum of 50 mg/ day when this dosage is > 50 mg/day. *...'
{{Drugswitch
| from = fluvoxamine
| to = doxepin
| stop =
* '''Day 0:''' gradually reduce dosage of fluvoxamine to a maximum of 50 mg/ day when this dosage is > 50 mg/day.
* '''Day 1:''' reduce dosage of fluvoxamine to a maximum of 25 mg/day.
| start =
Caution is necessary
* '''Day 1:''' simultaneously start administration of doxepin in a low dosage of 25 mg/day.
* '''Day 8:''' stop administration of fluvoxamine and continue administration of doxepin only. If necessary, increase dosage of doxepin.
| info =
* Fluvoxamine slows the metabolism of doxepin via CYP2D6, and possibly via CYP1A2 too.
* "Start low, go slow" is not required, but caution is necessary.}}
| from = fluvoxamine
| to = doxepin
| stop =
* '''Day 0:''' gradually reduce dosage of fluvoxamine to a maximum of 50 mg/ day when this dosage is > 50 mg/day.
* '''Day 1:''' reduce dosage of fluvoxamine to a maximum of 25 mg/day.
| start =
Caution is necessary
* '''Day 1:''' simultaneously start administration of doxepin in a low dosage of 25 mg/day.
* '''Day 8:''' stop administration of fluvoxamine and continue administration of doxepin only. If necessary, increase dosage of doxepin.
| info =
* Fluvoxamine slows the metabolism of doxepin via CYP2D6, and possibly via CYP1A2 too.
* "Start low, go slow" is not required, but caution is necessary.}}