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Combining-Risperidone-Lithium

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* Risperidone is principally metabolized by CYP2D6 to an active metabolite.
* Lithium is eliminated by the kidney for about 95%. Changes in the rate of excretion can cause unwanted effects.
* This combination of drugs may have possible synergistic effects. However, this combination will also have additive side effects. Dose adaptation will be recommended for this combination.
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