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{{Drugswitch | from = sertraline | to = nortriptyline| stop = * '''Day 0:''' gradually reduce dosage of sertraline to a maximum of 50 mg/day when this dosage is > 50 mg/day. * '''Day 1:''' reduce dosage of sertraline to a maximum of 25 mg/day. | start = Caution is necessary.* '''Day 1:''' simultaneously start administration of nortriptyline in a low dosage of 25 mg/day. * '''Day 8:''' stop administration of sertraline and only continue administration of nortriptyline in a dosage of 50 mg/day.* "Start low, go slow" is not required, but caution is necessary.| info = * Sertraline dose-dependently slows the metabolism of amitriptyline via CYP2D6. }}