* This combination The advantages of gabapentin include the lack of interactions with other drugs may have possible synergistic effectsin the cytochrome P450 system and the lack of protein binding. There are no reports for pharmacokinetic Since there is little risk of drug interactions. However, the combination will have additional side effectsuse with lithium is likely to be safe. <ref name=”freeman”> {{Pubmed|9433333|Freeman et al. Mood stabilizer Combinations: A Review of Safety and Efficacy. Am J Psychiatry 1998;155:12-21}}</ref>