838
edits
Changes
Created page with '{{Drugswitch | from = paroxetine | to = nortriptyline | stop = * '''Day 0:''' gradually reduce dosage of paroxetine to a maximum of 20 mg/day when this dosage is > 20 mg/day....'
{{Drugswitch
| from = paroxetine
| to = nortriptyline
| stop =
* '''Day 0:''' gradually reduce dosage of paroxetine to a maximum of 20 mg/day when this dosage is > 20 mg/day.
* '''Day 1:''' Reduce dosage of paroxetine to a maximum of 10 mg/day.
* '''Day 8:''' reduce dosage of paroxetine to 5 mg/day.
| start =
* '''Day 8:''' simultaneously start administration of nortriptyline in a low dosage of 25 mg/day.
* '''Day 15:''' stop administration of paroxetine and only continue nortriptyline in a dosage of 50 mg/day.
* “Start low, go slow” is not required, but caution is necessary.
| info = Paroxetine slows the metabolism of nortriptyline via CYP2D6. }}
| from = paroxetine
| to = nortriptyline
| stop =
* '''Day 0:''' gradually reduce dosage of paroxetine to a maximum of 20 mg/day when this dosage is > 20 mg/day.
* '''Day 1:''' Reduce dosage of paroxetine to a maximum of 10 mg/day.
* '''Day 8:''' reduce dosage of paroxetine to 5 mg/day.
| start =
* '''Day 8:''' simultaneously start administration of nortriptyline in a low dosage of 25 mg/day.
* '''Day 15:''' stop administration of paroxetine and only continue nortriptyline in a dosage of 50 mg/day.
* “Start low, go slow” is not required, but caution is necessary.
| info = Paroxetine slows the metabolism of nortriptyline via CYP2D6. }}