* Ziprasidone is metabolized by CYP3A4 and CYP1A2 (minor).<ref>Bazire S; Psychotropic drug directory, 2007</ref>
* This combination of drugs may have possible synergistic effects.
* Induction of CYP3A4 by carbamazepine may modestly influence the plasma level of ziprasidone. Ziprasidone dose modifications are unlikely to be necessary in patients receiving potent CYP450 3A4 inducers.<ref name="drugscom">