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* Lamotrigine does not cause a significant change in the pharmacokinetics of lithium. Start lithium according to the general dosing advice. <ref> {{Pubmed| 10971302 |Chen C at al, The effects of lamotrigine on the pharmacokinetics of lithium. Br J Clin Pharmacol 2000;50(3):193-5}}</ref>
| cave = * Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects. <ref name="drugscom">{{Drugscominteract|lithiumlamotrigine-with-lamotriginelithium-14301477-0-14771430-0|lamotrigine|lithium|lamotrigine}}</ref>
}}