| to = sertraline
| stop =
* Gradually reduce dosage of bupropion to a maximum of 150 mg/ day. * When a dosage of 150 mg/day is reached, stop administration.{{StopBupropion1}}| start = {{StartAntidepressant}}* No wash-out period is needed. | info =* Start Safe target dose sertraline the next day in normal dosage of 20 = 100 mg/day.| info = * Bupropion and its metabolites have long elimination times, so plasma concentrations will reduce gradually.}}