838
edits
Changes
Created page with '{{Drugswitch | from = duloxetine | to = nortriptyline | stop = * '''Before day 0:''' gradually reduce dosage of bupropion to a maximum of 60 mg/day. * '''Day 1:''' reduce the...'
{{Drugswitch
| from = duloxetine
| to = nortriptyline
| stop =
* '''Before day 0:''' gradually reduce dosage of bupropion to a maximum of 60 mg/day.
* '''Day 1:''' reduce the dosage of duloxetine to 30 mg/day.
| start =
* '''Day 1:''' simultaneously start administration of nortriptyline in a low dosage of 25 mg/day.
* '''Day 8:''' stop administration of duloxetine and increase the dosage of nortriptyline to 50 mg/day.
| info =
* Duloxetine slows the metabolism of nortriptyline by CYP2D6.
* Caution is necessary at the start of administration of nortriptyline. }}
| from = duloxetine
| to = nortriptyline
| stop =
* '''Before day 0:''' gradually reduce dosage of bupropion to a maximum of 60 mg/day.
* '''Day 1:''' reduce the dosage of duloxetine to 30 mg/day.
| start =
* '''Day 1:''' simultaneously start administration of nortriptyline in a low dosage of 25 mg/day.
* '''Day 8:''' stop administration of duloxetine and increase the dosage of nortriptyline to 50 mg/day.
| info =
* Duloxetine slows the metabolism of nortriptyline by CYP2D6.
* Caution is necessary at the start of administration of nortriptyline. }}