[[File{{Drugswitch | from = vortioxetine | to = tranylcypromine | stop = * '''Day 1:Empty''' reduce dosage of vortioxetine to 5 mg/day.jpg]]* '''Day 7:''' stop administration of vortioxetine.| start = * '''Day 8-21:''' a wash-out period of two weeks is necessary.* '''Day 22:''' Start administration of tranylcypromine in low dosage of 20 mg/day for one week.* '''Day 29:''' after this week the dosage of tranylcypromine can be increased if necessary. | caveat = * Occurrence of serotonin syndrome is reported when a wash-out period (of two weeks) is not considered. }}