[[File{{Drugswitch | from = amitriptyline | to = vortioxetine | stop = * '''Before day 1:Empty''' gradually reduce dosage of amitriptyline to a maximum of 50 mg/day.jpg]]* '''Day 1:''' reduce dosage of amitriptyline to 25 mg/day.* '''Day 8:''' stop administration of amitriptyline.| start = * A wash-out period is not necessary.* Start administration of vortioxetine the next day in a dosage of 10 mg/day.| info = * {{theorSS}}}}