[[File{{Drugswitch | from = fluvoxamine| to = vortioxetine | stop = * '''Before day 1:Empty''' gradually reduce dosage of fluvoxamine to a maximum of 50 mg/day, when this dosage is > 50 mg/day.jpg]]* '''Day 1:''' when a dosage of 50 mg/day is reached, stop administration| start = * A wash-out period is not necessary, but care is needed.* '''Day 1:''' Start administration of vortioxetine the next day in a dosage of 10 mg/day.| info =* Fluvoxamine is a strong inhibitor of CYP2C9, which metabolizes vortioxetine. * Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.}}