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Bupropion-vortioxetine

163 bytes removed, 11:48, 4 August 2023
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| to = vortioxetine
| stop =
* '''Before day 1:''' Gradually reduce dosage of bupropion to a maximum of 150 mg/ day. * '''Day 1:''' When a dosage of 150 mg/day is reached, stop administration.{{StopBupropion}}
| start =
* '''Day 1:''' start administration Start vortioxetine with a dosage of 5 mg/day.* ''' Day 8: ''' increase dosage of vortioxetine in to a normal dosage of 10 mg/day.
| info =
* Bupropion and its metabolites have long elimination times (t1/2: 20-37 hours), so plasma concentrations will reduce gradually.slows the metabolism of vortioxetine via CYP2D6
}}