[[File{{Drugswitch | from = mirtazapine| to = vortioxetine | stop = * '''Before day 1:Empty''' gradually reduce dosage of mirtazapine to a maximum of 30 mg/day, when this dosage is > 30 mg/day.jpg]]* '''Day 1:''' reduce the dosage of 30 mg/day to 15 mg/day.* '''Day 8:''' stop administration of mirtazapine. | start = * A wash-out period is not necessary.* '''Day 8:''' start administration of vortioxetine in a dosage of 10 mg/day.| info = * Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.}}