[[File{{Drugswitch | from = trazodone| to = vortioxetine | stop = * '''Before day 1:Empty''' gradually reduce dosage of trazodone to a maximum of 150 mg/day, when this dosage is > 150 mg/day.jpg]]* '''Day 1:''' reduce the dosage of trazodone to 75-100 mg/day.* '''Day 8:''' when a dosage of 75 mg/day is reached, stop administration| start = * A wash-out period is not necessary.* '''Day 8:''' start administration of vortioxetine in a normal dosage of 10 mg/day.| info = * Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.* The content of trazodone in the tablet, for example 100 mg or 150 mg, determines which exact doses are given. }}