| to = bupropion
| stop =
* Gradually decrease the dosage of tranylcypromine with 10-20 mg/week. * When a dosage of 10 mg/day is reached, stop administration.{{Dec25p3d}}
| start =
* '''Day 1-14:''' a wash-out period of two weeks is necessary. * '''Day 15:''' start bupropion after this period in a normal dosage of 150 mg/day.{{Inc25p3do50pw}}
| info =
* Occurrence of the serotonin syndrome is possible without a wash-out period.* The wash-out period is necessary for the MAO enzymes to restore their function.{{reviewTcrestore}}
}}