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Venlafaxine-mianserine

572 bytes added, 19:35, 5 May 2009
Created page with '{{Drugswitch | from = venlafaxine | to = mianserine | stop = * '''Day 0:''' gradually reduce dosage of duloxetine to a maximum of 75 mg/day. * '''Day 1:''' reduce a dosage o...'
{{Drugswitch
| from = venlafaxine
| to = mianserine
| stop =
* '''Day 0:''' gradually reduce dosage of duloxetine to a maximum of 75 mg/day.
* '''Day 1:''' reduce a dosage of venlafaxine from 75 mg/day to 37,5 mg/day.
| start =
* '''Day 1:''' simultaneously start administration of mianserine in a dosage of 30 mg/day.
* '''Day 8:''' stop administration of venlafaxine and continue administration of mianserine only. If necessary, increase dosage of mianserine to 40-60 mg/day.
| info =
* Venlafaxine is a weak inhibitor of CYP2D6, which metabolizes mianserine. }}
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