| to = sertraline
| stop =
* Gradually reduce dosage of bupropion to a maximum of 150 mg/ day. * When a dosage of 150 mg/day is reached, stop administration.{{StopBupropion1}}
| start =
* ''' Day 2: ''' Start sertraline the next day in normal dosage of 50 mg/day.
* ''' After 3 weeks:''' If necessary increase dosage gradually to 200 mg/day
| info =
* No wash-out period is needed.
* Start sertraline the next day in normal dosage of 50 mg/day.
| info =
* Bupropion and its metabolites have long elimination times, so plasma concentrations will reduce gradually.
{{review}}
}}