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{{Inc25p3d2}}* '''Day 1-3:''' start Start administration of amitriptyline in a low dosage of 25 mg/day.* '''Day 4:''' increase dosage of amitriptyline to 50 mg/day and continue slowly increasing the dosage depending on the condition of the patient.
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* Bupropion slows the metabolism of amitriptyline via CYP2D6.