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Moclobemide-vortioxetine

113 bytes removed, 08:00, 21 October 2015
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* '''Before day 1:''' gradually reduce dosage of moclobemide to a maximum of 300 mg/day. * '''Day 1:''' reduce the dosage of moclobemide to 150 mg/day.* '''Day 8:''' stop administration of moclobemide.{{stopMoclobemide}}
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* '''Day 8-9:''' a wash-out period of two days is necessary. * '''Day 10:''' start administration of vortioxetine in a normale dosage of 10 mg/day. 
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* Because of short halve life of moclobemide after stopping, the next antidepressant can start next day.
* A wash-out period is not necessary.
* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.
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