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* '''Day 1516:''' start administration of agomelatine in a dosage of 25 mg/day.* '''Day 2223:''' if necessary, increase dosage of agomelatine to 50 mg/day.
<ref name="agoswitch"> {{Pubmed|20196187|McAllister-Williams RH et al. The use of antidepressants in clinical practice: focus on agomelatine. Hum Psychopharmacol. 2010 Mar 1;25(2):95-102}}</ref>