| stop =
{{stopFluoxetine1}}
* '''Before day 1:''' Gradually reduce dosage of fluoxetine to a maximum of 20 mg/ day, when this dosage is > 20 mg/day.
* '''Day 1:''' When a dosage of 20 mg/day is reached, stop administration.
| start =
Caution is necessary for at least four weeks.
* '''Day 12:''' start administration of amitriptyline in a low dosage of 25 mg/day. * '''Day 1415:''' increase dosage of amitriptyline to 50 mg/day.* '''Day 2829:''' gradually increase dosage of amitriptyline.
| info =
* Fluoxetine and norfluoxetine slow the metabolism of amitriptyline via CYP2D6.