* '''Before day 1:''' gradually reduce dosage of escitalopram to a maximum of 10 mg/day, when this dosage is > 10 mg/day. * '''Day 1:''' reduce dosage of escitalopram to a maximum of 5 mg/day. * '''Day 8:''' stop administration of escitalopram.{{stopEscitalopram}}
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* '''Day 8:''' no wash-out period is needed. Start administration of clomipramine in a low dosage of 25-50 mg/day.