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Amitriptyline-paroxetine

183 bytes removed, 12:51, 2 November 2015

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* '''Before day 1:''' gradually reduce dosage of amitriptyline to a maximum of 50 mg/day.* '''Day 1:''' reduce dosage of amitriptyline to 25 mg/day.* '''Day 8:''' stop dosage of amitriptyline.{{stopAmitriptyline1}}

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* '''Day 8:''' start administration of paroxetine in a normal dosage of 20 mg/day.

* {{theorSS}}

* Paroxetine is a strong inhibitor of CYP2D6, which metabolizes amitriptyline.

~~{{review}}~~

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Anoek

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Psychiatrienet β

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Amitriptyline-paroxetine

Psychiatrienet ^β