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Dosulepine-duloxetine

297 bytes removed, 13:16, 2 November 2015
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* '''Before day 1:''' gradually reduce dosage of dosulepine to a maximum of 75 mg/day.* '''Day 1:''' reduce dosage of dosulepine to 50 mg/day.* '''Day 3:''' reduce dosage of dosulepine to 25 mg/day.* '''Day 7:''' stop dosulepine{{stopDosulepine}}
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* '''Day 89:''' start administration of duloxetine in a normal dosage of 60 mg/day.
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* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.{{theorSS}}
* Duloxetine is a inhibitor of CYP2D6, which metabolizes dosulepine.
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