| stop = * '''Before day 1:''' gradually reduce dosage of trazodone to a maximum of 150 mg/day{{StopSSRI, when this dosage is > 150 mg/day. * '''Day 1:''' reduce dosage of trazodone to 75-100 mg/day.* '''Day 8:''' stop administration of trazodone.SNRI}}| start = {{StartAntidepressant}}* A wash-out period is not necessary, but care is needed.| info =* '''Day 8:''' start administration of Safe target dose paroxetine in a normal dosage of = 20 mg/day.| info = * Paroxetine is a strong inhibitor of CYP2D6, which metabolizes trazodone.* The content of trazodone in the tablet, for example 100 mg or 150 mg, determines which exact doses are given. {{reviewtheorSS}}