| to = amitriptyline
| stop =
* '''Before day 1:''' gradually reduce dosage of duloxetine to a maximum of 60 mg/ day, when this dosage is > 60 mg/day. * '''Day 1:''' reduce dosage of duloxetine to a maximum of 30 mg/day. * '''Day 8:''' stop administration of duloxetine.{{stopDuloxetine}}
| start =
A wash-out period of one week is necessary.* '''Day 89-1415:''' wash-out periodof one week is necessary. * '''Day 1516:''' start administration of amitriptyline in a low dosage of 25 mg/day. | info = * Start low, go slow for amitriptyline!{{review}}
* Duloxetine is a moderate inhibitor of CYP2D6, which metabolizes amitriptyline. }}