| to = trazodone
| stop =
* '''Day 1:''' reduce dosage of vortioxetine to 5 mg/day.* '''Day 8:''' stop administration of vortioxetine.{{stopVortioxetine}}
| start =
* No wash-out period is needed.
* '''Day 89:''' start trazodone in a dosage of 100-150 mg/day.
* If necessary, increase the dosage of trazodone gradually to a maximum of 400 mg/day.
| info =
* {{theorSS}}
}}