{{Inc25p3d2}} * '''Day 1:''' start administration of dosulepine in a low dosage of 25 mg/day. * '''Day 8:''' increase dosage of dosulepine to a dosage of 75 mg/day.
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* Bupropion slows the metabolism of dosulepine via CYP2D6.
* Caution is necessary at the start of administration of dosulepine.