Stop-doxepin

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Doxepin
Type antidepressant
Group TCA
links
ATC-code N06AA12
Medscape Doxepin
PubChem 3158
PubMed Doxepin
Drugs.com doxepin
Kompas (Dutch) Doxepin
Wikipedia Doxepin


Nietinrijdenbord.png Stop doxepin
  • In general after long-term maintenance treatment, the best is to reduce the dose by about 25% every 4-6 weeks. An apt pharmaceutical dose (tablet, capsule, mixture) is not always available. In these cases one should be creative with dosing.[2][3]
  • Another, more risky, possibility is being at a certain dose to use the following scheme:[4]
  • 150 mg/day:
  • Day 1: reduce dosage of doxepin to 100 mg/day.
  • Day 8: reduce dosage of doxepin to 75 mg/day.
  • Day 15: reduce dosage of doxepin to 50 mg/day.
  • Day 22: reduce dosage of doxepin to 25 mg/day.
  • Day 30: stop the administration of doxepin.



  1. 1.0 1.1 1.2 1.3 1.4 KNMP; Informatorium Medicamentorum 2023; Monografie "doxepine" (Dutch)
  2. The UK Drug and Therapeutics Bulletin; 1999;37:49-52
  3. Editor: please note that not all dosages are available in pharmacy. So now and then you should be creative.
  4. Bazire S, Psychotropic Drug Directory 2010. Aberdeen: HealthComm UK Ltd; 2010.
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